Caught on Film: The Secret Lives of Dendrites in the Tadpole Optic Tectum
نویسنده
چکیده
Much is known about the functions and properties of neuronal dendrites, but rarely has dendritic activation been monitored while the dendrite performs a computational task. In this issue of Neuron, Bollmann and Engert demonstrate that different regions of a dendrite in the tadpole optic tectum are tuned to stimuli in different locations of the visual field. Their study is the first direct demonstration that dendritic regions act as semi-independent functional units during sensory processing in a vertebrate central nervous system.
منابع مشابه
The horizontal brain slice preparation: a novel approach for visualizing and recording from all layers of the tadpole tectum.
The Xenopus tadpole optic tectum is a multisensory processing center that receives direct visual input as well as nonvisual mechanosensory input. The tectal neurons that comprise the optic tectum are organized into layers. These neurons project their dendrites laterally into the neuropil where visual inputs target the distal region of the dendrite and nonvisual inputs target the proximal region...
متن کاملInnovative Methodology The horizontal brain slice preparation: a novel approach for visualizing and recording from all layers of the tadpole tectum
Hamodi AS, Pratt KG. The horizontal brain slice preparation: a novel approach for visualizing and recording from all layers of the tadpole tectum. J Neurophysiol 113: 400–407, 2015. First published October 15, 2014; doi:10.1152/jn.00672.2014.—The Xenopus tadpole optic tectum is a multisensory processing center that receives direct visual input as well as nonvisual mechanosensory input. The tect...
متن کاملTitle: the Horizontal Brain Slice Preparation: a Novel Approach for Visualizing And
1 recording from all layers of the tadpole tectum 2 3 Abbreviated title: Novel tadpole brain preparation for studying the tectum 4 5 Author names: Institutes of Health under grant number P30GM32128. We thank Dr. Carlos 26 Aizenman and Dr. Mayank Mehta for their help with the current-source density 27 analysis and Dr. Qian-Quan Sun for helpful comments on the manuscript. 1 38 The Xenopus tadpole...
متن کاملAn NMDA receptor-dependent mechanism for subcellular segregation of sensory inputs in the tadpole optic tectum
In the vertebrate CNS, afferent sensory inputs are targeted to specific depths or layers of their target neuropil. This patterning exists ab initio, from the very beginning, and therefore has been considered an activity-independent process. However, here we report that, during circuit development, the subcellular segregation of the visual and mechanosensory inputs to specific regions of tectal ...
متن کاملTitle: Region-specific Regulation of Voltage-gated Intrinsic Currents in the 1 Developing Optic Tectum of the Xenopus Tadpole 2 3 Abbreviated Title: Region-specific Regulation of Intrinsic Currents 4
National Institutes of Health under grant number P30GM32128. We thank Diem 25 Thu Pham for help with statistical analysis. Abstract 32 1 Across the rostrocaudal axis of the Xenopus tadpole optic tectum exists a 33 developmental gradient. This gradient has served as a useful model to study 34 many aspects of synapse and dendrite maturation. To compliment these studies, 35 we characterized how th...
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ورودعنوان ژورنال:
- Neuron
دوره 61 شماره
صفحات -
تاریخ انتشار 2009